Bispectral Index versus Minimum Alveolar Concentration for Prevention of Intraoperative Awareness

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Bispectral index versus minimum alveolar concentration for prevention of intraoperative awareness: does a practical controlled trial provide CERtainty?

A PPROXIMATELY half of all medical care provided in the United States is based on insufficient scientific evidence and may even be of “uncertain or questionable value.” This realization has spurred interest and extensive government funding in comparative effectiveness research (CER) with the ultimate goal to improve the effectiveness, efficacy, and efficiency of health care. To date, few initia...

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Concurrence of Intraoperative Hypotension, Low Minimum Alveolar Concentration, and Low Bispectral Index Is Associated with Postoperative Death.

BACKGROUND An intraoperative concurrence of mean arterial pressure less than 75 mmHg, minimum alveolar concentration less than 0.8, and bispectral index less than 45 has been termed a "triple low" state. An association between triple low and postoperative mortality has been reported but was not replicated in a subsequent study. The authors pooled existing data from clinical trials to further ev...

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Protocol for the "Michigan Awareness Control Study": A prospective, randomized, controlled trial comparing electronic alerts based on bispectral index monitoring or minimum alveolar concentration for the prevention of intraoperative awareness

BACKGROUND The incidence of intraoperative awareness with explicit recall is 1-2/1000 cases in the United States. The Bispectral Index monitor is an electroencephalographic method of assessing anesthetic depth that has been shown in one prospective study to reduce the incidence of awareness in the high-risk population. In the B-Aware trial, the number needed to treat in order to prevent one cas...

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Relationships between Bispectral Index, Implicit Memory, Dream Recall and Minimum Alveolar Concentration in Blended Anaesthesia

The decreased responsiveness to stimulation defines the depth of anaesthesia which is a balance between effects of anaesthetic drugs and surgical stimulations. Awareness is a rare occurrence with an incidence of 0,1-0,2 %1, defined as postoperative recall of events occurring during general anaesthesia. This memory can be traumatic and may result in developing a chronic posttraumatic stress diso...

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ژورنال

عنوان ژورنال: Anesthesiology

سال: 2012

ISSN: 0003-3022

DOI: 10.1097/aln.0b013e3182690586